FISIOPATOLOGIA DIARREA POR ROTAVIRUS PDF

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Directory of Open Access Journals Sweden. Full Text Available Objetivo. Comparar la gravedad de la diarrea por rotavirus RV y por no rotavirus. Full Text Available Objective. To assess the disease burden of rotavirus diarrhea in Peru as well the need for and the potential cost savings with a rotavirus vaccine in that country. To assess the burden of rotavirus diarrhea in Peru, we reviewed published and unpublished reports where rotavirus was sought as the etiologic agent of diarrhea in children.

Rotavirus detection rates obtained from these studies were combined with diarrhea incidence rates from a number of national surveys in order to estimate both the burden of rotavirus diarrhea in the country and its associated medical costs. Rotavirus is a significant cause of morbidity and mortality in Peruvian children. In their first 5 years of life, an estimated 1 in 1. Per year, this represents approximately cases, 64 clinic visits, 30 hospitalizations, and 1 deaths.

Rotavirus immunization provides the prospect of decreasing the morbidity and mortality from diarrhea in Peru, but a vaccine regimen would have to be relatively inexpensive, a few dollars or less per child. Future cost-effectiveness analyses should explore the total costs medical as well as indirect or societal associated with rotavirus diarrhea. Newly licensed vaccines should be tested according to both their ability to avert deaths and their efficacy with fewer than three doses.

All three of these factors could increase the cost savings associated with a rotavirus vaccine. Estos datos. From October to March , 92 out of There were not differences of rotavirus incidence between age groups. Although in Paraguay, rotavirus infections in children less than 5 years old present a seasonal peak pattern since June to October, in adults rotavirus was present throughout the year with the same frequency. Results presented here reinforce the notion that rotavirus should be considered in the differential diagnosis of diarrhea in adults.

Turcios-Ruiz; Claudia E. Andrus; Paul W. Stupp; Joseph S. Bresee; Roger I. METHODS: Data were collected from computerized records of all children Outbreak of rotavirus gastroenteritis with high mortality, Nicaragua, Brote de gastroenteritis por rotavirus con alta mortalidad, Nicaragua, In those states that received the HRV early in , diarrhea mortality decreased between OBJECTIVE: Determine the epidemiological profile of outbreaks of acute diarrheal disease caused by rotavirus RV occurring in pediatric patients, based on a critical review of the literature published between and In the studies that met the inclusion criteria, possible confounding factors were identified and risks of bias were attributed based on the.

El promedio de gasto fecal en el grupo AL fue CDC's Dr. Jon Gentsch discusses rotaviruses , the most important cause of severe gastroenteritis in children less than five years of age. Essentially, all children around the world get the disease during the first few years of life. Se administraron dosis de vacuna o de placebo a la edad de 1, 3 y 5 meses. Estos resultados.

Diarrea y micronutrientes. Ambas vacunas ya han pasado exitosamente por los estudios de fases I y II y en estos momentos se llevan a cabo extensos estudios de fase III. La vacuna fue introducida en el Programa Ampliado de Inmunizaciones en enero de To evaluate the safety and effectiveness of two oral rehydration techniques.

Material and Methods. A randomized clinical trial was conducted at the oral rehydration unit of Hospital Infantil de Mexico "Federico Gomez", between September and June Forty patients five-year old and younger children, dehydrated due to acute diarrhea, were given oral rehydration solution ORS ad libitum AL group; another forty patients received ORS in fractionated doses FD group.

Clinical characteristics were similar in both groups. Results are presented as. Fueron excluidos aquell Le siguieron en importancia Campylobacter spp. In four cities of Venezuela a study was carried out to evaluate the epidemiological, clinical, and etiological characteristics of acute diarrhea in children under 5 years of age.

The study was done between June and May and involved children who were seen in a hospital, 2 with diarrhea and controls.

The Fisher exact test was used for the statistical analysis of the results. Following in importance were Campylobacter spp. The importance of age was confirmed as a determining factor in the prevalence and severity of diarrhea. Diarrea del viajero asociada a Aeromonas hydrophila. Full Text Available Aeromonas hydrophila es una bacteria que se encuentra frecuentemente en aguas dulces y salobres.

Rotavirus Symptoms. Rotavirus Treatment. Sobrevivieron a la etapa aguda de la enfermedad 9 pacientes. Objetivo: Indagar sobre los conocimientos, actitudes, Rotavirus Vaccine.

Why get vaccinated? Rotavirus is a virus that causes diarrhea, mostly in babies and young children. The diarrhea can be severe, and lead Before rotavirus vaccine, rotavirus disease was a common EDA es causada por diversos agentes. Entre los que se asocian de tipo bacteriano, parasitario y principalmente viral. Resultados: En general virus fueron detectados entre las muestras, en casos y 60 en controles.

El virus con mayor prevalencia fue norovirus GII con Norovirus GI, astrovirus y adenovirus fueron identificados en 3. Mediadores y moduladores extracelulares del transporte intestinal. This a review of some important aspects of the physiopathology of diarrhea. A description is made of the intestinal physiopathology, including the anatomy of the intestine and of its surface of absorption, as well as the functional structure of the intestinal mucosa: the normal physiopathology of the intestinal fluids; the mechanism of absorption of water and electrolites; the absorption of sodium by electrogenic difussion, joined to the chloride ion; the interchange with the hydrogen ion and attached to organic substances, such as glucose, aminoacids and some oligopeptides; the intestinal secretion of water and electrolites; the intracellular control of secretion, the extracellular mediators and modulators of intestinal transport; the factors that increase absorption and reduce secretion; the factors that stimulate secretion and absorption; and the physiopathological mechanism of diarrhea.

The classification of acute infectious diarrhea in aqueous. Rotavirus Infections. Rotavirus is a virus that causes gastroenteritis. Symptoms include severe diarrhea, vomiting, fever, and dehydration. Almost all Infections happen most often Las probabilidades y los costos unitarios se tomaron de investigaciones publicadas y de los datos oficiales nacionales.

Rotavirus infection. Crawford, Sue E. Rotavirus primarily infects enterocytes and induces diarrhoea through the destruction of absorptive enterocytes leading to malabsorption , intestinal secretion stimulated by rotavirus non-structural protein 4 and activation of the enteric nervous system. In addition, rotavirus infections can lead to antigenaemia which is associated with more severe manifestations of acute gastroenteritis and viraemia, and rotavirus can replicate in systemic sites, although this is limited.

Reinfections with rotavirus are common throughout life, although the disease severity is reduced with repeat infections. The immune correlates of protection against rotavirus reinfection and recovery from infection are poorly understood, although rotavirus -specific immunoglobulin A has a role in both aspects. The management of rotavirus infection focuses on the prevention and treatment of dehydration, although the use of antiviral and anti-emetic drugs can be indicated in some cases.

Rotavirus vaccines. Rotavirus is the leading cause of severe diarrhea among children rotavirus vaccines have been efficacious and effective, with many countries reporting substantial declines in diarrheal and rotavirus -specific morbidity and mortality.

However, the full public health impact of these vaccines has not been realized. Most countries, including those with the highest disease burden, have not yet introduced rotavirus vaccines into their national immunization programs.

Research activities that may help inform vaccine introduction decisions include 1 establishing effectiveness, impact, and safety for rotavirus vaccines in low-income settings; 2 identifying potential strategies to improve performance of oral rotavirus vaccines in developing countries, such as zinc supplementation; and 3 pursuing alternate approaches to oral vaccines, such as parenteral immunization.

Policy- and program-level barriers, such as financial implications of new vaccine introductions, should be addressed to ensure that countries are able to make informed decisions regarding rotavirus vaccine introduction. De muestras analizadas, se encontraron 40 muestras positivas, con una tasa de prevalencia de Incidencia y factores de riesgo para adquirir diarrea aguda en una comunidad rural de la selva peruana.

Resultados: Fueron observados 18 casos de diarrea aguda; la incidencia fue La edad media de los casos fue de Los factores de riesgo para adquirir diarrea fueron: consumo de alimentos crudos, RR: 2. No hubo diferencia en el tiempo de residencia en la comunidad entre casos y controles, media de 5.

METHODS: An economic model was constructed using epidemiological data from published articles, national health administration studies, and country-specific cost estimates. For each of the eight countries, the model estimated the rotavirus outcomes for the birth cohort during the first five years of life.

The main outcome measures included health care costs, transportation costs, lost wages, and disease burden expressed in disability-adjusted life years. Estimates were expressed in US dollars. Sensitivity analyses evaluated the impact of specific variables on the medical cost of treating rotavirus.

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Acute gastroenteritis: clinical presentation and etiology in children hospitalized at the Children's Hospital of Pereira Rossell Hospital Center in Facultad de Medicina. Asistente interino Depto. Asistente Depto. Declaramos no tener conflictos de intereses. Fecha recibido: 14 de mayo de Fecha aprobado: 25 abril de

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